"The HHS PHEMCE Strategy, published in the Federal Register on March 20, 2007, described a framework of strategic policy goals and objectives for identifying medical countermeasure requirements and establishing priorities for medical countermeasure evaluation, development and acquisition. These strategic policy goals and objectives were used to establish the Four Pillars upon which this HHS Public Health Emergency Medical Countermeasures Enterprise Implementation Plan (HHS PHEMCE Implementation Plan) is based.... (1) Pillar One: Identify and assess CBRN threats. (2) Pillar Two: Assess medical/public health consequences. (3) Pillar Three: Establish medical countermeasure requirements that incorporate assessments of current levels of preparedness, concepts of utilization, and product specifications. (4) Pillar Four: Identify and prioritize near-, mid-, and long-term development and acquisition programs informed by assessment of the maturity of the product development pipeline and estimated costs. (HHS, PHEMCE Implementation Plan, 2007, p. 6)