Skin Irritation 1


Skin Irritation 1 : Ratings corresponding to the following definitions are derived from data obtained from the test methods as described in the CFR 16 1500.41 and or NAS publication 1138 and categories of toxicity as described in 16 CFR 1500.3. (1) PRACTICALLY NON-IRRITATING: The undiluted product causes no noticeable irritation or causes slight inflammation (edema and erythema skin reaction values of 0 to 1) of intact or abraded skin of rabbits during the study period. Primary irritation index of 0 - 1.9. (2) MODERATELY IRRITATING: The undiluted product causes well-defined inflammation (edema and erythema skin reaction values of 2) during the study period. Primary irritation index of 2 - 4.9. (3) PRIMARY SKIN IRRITANT: The undiluted product cause moderate to severe inflammation (edema and erythema skin reaction values of 3 or 4) of the intact or abraded skin of rabbits during the study period. Primary irritation index of 5 or more. (4) CORROSIVE: The undiluted product causes visible destruction or irreversible alterations of the tissue structure at the site of contact on intact or abraded skin of rabbits during the study period
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