A family of separation processes, based on continuous liquid chromatography. The adsorbent, chosen for its selectivity and usually a zeolite, is contained in a chromatographic column with a number of ports spaced along its length. These ports, operated by a proprietary rotary valve, function alternately as inlets and outlets and thus permit simulated countercurrent liquid solid adsorption to be operated in a continuous mode. Variations of this process for specific mixtures, each with its preferred adsorbent and desorbent, are described under their own names, viz. Cymex, Ebex, Molex, Olex, Parex, Sarex, Sorbutene