Toxicokinetics 4
Toxicokinetics 4 : The study of the movement of toxic substance within the body. It refers to the absorption, distribution, metabolism and excretion of xenobiotics (substances "foreign" to the body). Toxicokinetics takes into consideration differences in susceptibility among individuals. The factors to consider in these processes are those of (1) bioavailability, (2) absorption, (3) distribution, (4) metabolism and (5) excretion and how they may be affected by genomic or environmental factors or combinations thereof. It also encompasses the relationship between the dose that enters the body and the level of the toxic substance in any biological sample
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