Uric Acid


Uric Acid :

Increase in serum uric acid is seen idiopathically and in renal failure, disseminated neoplasms, toxemia of pregnancy, psoriasis, liver disease, sarcoidosis, ethanol consumption, etc. Many drugs elevate uric acid, including most diuretics, catacholamines, ethambutol, pyrazinamide, salicylates, and large doses of nicotinic acid. Decreased serum uric acid level may not be of clinical significance. It has been reported in Wilson's disease, Fanconi's syndrome, xanthinuria, and (paradoxically) in some neoplasms, including Hodgkin's disease, myeloma, and bronchogenic carcinoma. Uric acid is formed in the breakdown of nucleoproteins in the tissues, and excreted in the urine. It is found in the bloodstream within a normal range (2 - 8 milligrams per deciliter). Elevated blood uric acid levels can put patients at an increased risk for kidney stone formation

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