Valeriana Officinalis. Valerian is a root that has been used since ancient Greek times for its relaxing, sedative effects. Aside from the important valerenic acid, over 120 other important components have been identified from the root and its essential oil. Safe and effective anti-anxiety agent and sedative for treatment of restlessness and sleep disturbances resulting from nervous conditions. Those with impaired kidney or liver functions should not take valerian except under a physician's supervision. Valerian can interact with alcohol, certain antihistamines, muscle relaxants, psychotropic drugs and narcotics