Bile


Bile : Yellowish, brown, or green fluid made by the liver; in the small intestine, it aids in digestion, function is to remove waste from the liver and break down fats as food is digested. 2. Fluid secreted by the liver and poured into the small intestine via the bile ducts. Important constituents are conjugated bile salts, cholesterol, phospholipid, bilirubin diglucuronide, and electrolytes. Bile is alkaline due to its bicarbonate content, golden brown to greenish yellow in color, and has a bitter taste. Hepatic bile secreted by the liver, is concentrated in the gallbladder. Its formation depends on active secretion by liver cells into the bile canaliculi. Excretion of bile salts by liver cells and secretion of bicarbonate rich fluid by ductular cells in response to secretin are the major factors which normally determine the volume of secretion. Conjugated bile salts and phospholipid normally dissolve cholesterol in a mixed micellar solution. In the upper small intestine, bile is in part responsible for alkalinizing the intestinal content, and conjugated bile salts play an essential role in fat absorption by dissolving the products of fat digestion (fatty acids and monoglycerides) in water soluble micelles. Also Called gall
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