Bioavailability 02
Bioavailability 02 : (a) The state of being capable of being absorbed and available to interact with the metabolic processes of an organism. Typically a function of chemical properties, physical state of the material to which an organism is exposed, and the ability of the individual organism to physiologically take up the chemical. Also, the term used for the fraction of the total chemical in the environmental which is available for uptake by organisms. [AIHA, 2000: Risk Assessment Principles for the Industrial Hygienist, attributed to USEPA 1992a]; (b) The degree to which a substance becomes available to the target tissue after administration or exposure. [IRIS, 1999: Glossary of IRIS Terms]; (c) The state of being capable of being absorbed and available to interact with the metabolic processes of an organism. Bioavailability is typically a function of properties of agents, physical state of the material to which an organism is exposed, and the ability of the individual organism to physiologically take up the agent. [REAP, 1995: Residential Exposure Assessment Project]; (d) The state of being capable of being absorbed and available to interact with the metabolic processes of an organism. Bioavailability is typically a function of chemical properties, physical state of the material to which an organism is exposed, and the ability of the individual organism to physiologically take up the chemical. [USEPA, 1992: GL for Exposure Assessment] [USEPA, 1992a: Dermal Exposure Assessment]; (e) Degree of ability to be absorbed and ready to interact in organism metabolism. [USEPA, 1997a: EPA Terms of Environment]
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