Bioavailability 13
Bioavailability 13 :
(1) Extent to which a substance to which the body is exposed (by ingestion, inhalation, injection, or skin contact) reaches the systemic circulation, and the rate at which this occurs. Syn: Biological Availability, Physiological Availability. (2) Pharmacokinetic term relating systemic exposure from extravascular exposure (ev) to that following intravenous exposure (iv) by the equation: F = AUCev*Div / AUCiv*Dev where F is the bioavailability, AUCev and AUCiv are the areas under the plasma concentration time curve following extravascular and intravenous administration and Dev and Div are the administered extravascular and intravenous doses
No records Found