Biological Half-life (t1/2) 04
Biological Half-life (t1/2) 04 : The term which is used for the time required for the amount of a particular substance in a biological system to be reduced to one half of its value by biological processes when the rate of removal is approximately exponential. Substances with a long biological half-life will tend to accumulate in the body and are, therefore, particularly to be avoided. Substances with a short biological half-life may accumulate if some becomes tightly bound, even if most is cleared from the body rapidly. There is also the possibility of cumulative effects of chemicals which have a short residence time in the body
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