Ablation 5


Ablation 5 : Medicine: The procedure is used in the treatment ofcoronary heart disease to restore blood flow. Radiofrequency ablation (RFA) is a method of removing aberrant tissue from within the body via minimally invasive procedures. I. e. , RFA in an electrophysiology study to remove cells that are issuing abnormal electrical activity leading to arrhythmia. Bone marrow ablation is a process whereby the human bone marrow cells are eliminated in preparation for a bone marrow transplant. This is performed using high-intensity chemotherapy and total body irradiation. As such it has nothing to do with the vaporization techniques described in the rest of this article. Ablation of brain tissue is used for treating certain neurological disorders, particularly Parkinson's disease, and sometimes for psychiatric disorders as well. Recently, some researchers reported successful results with genetic ablation. In particular, genetic ablation is potentially a much more efficient method of removing unwanted cells, such as tumor cells, because large numbers of animals lacking specific cells could be generated. Genetically ablated lines can be maintained for a prolonged period of time and shared within the research community. Researchers at Columbia University report of reconstituted caspases combined from C. elegans and humans, which maintain a high degree of target specificity. The genetic ablation techniques described could prove useful in battling cancer
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