Reference Exposure Concentration (RfC)
Reference Exposure Concentration (RfC) :
An estimate, derived by the US EPA with an uncertainty spanning perhaps an order of magnitude) of a dailyexposure to the human population, (including sensitive subgroups) that is likely to be without appreciable risk of deleterious effects during a lifetime of exposure. The RfC is derived from a no or lowest observed adverse effect level from human or animal exposures, to which uncertainty or "safety" factors are applied
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