Association between the physicochemical properties of a substance and/or the properties of its molecular substructures and its biological properties including its toxicity. See also: quantitative structure-activity relation (QSAR)
International Union of Pure and Applied Chemistry IUPAC, Glossary for Chemists of Terms Used in Toxicology, Prepared for publication by J.H. Duffus, NC., USA 1993. http://www.inchem.org/documents/harmproj/harmproj/ harmproj1.pdf & http://old.iupac.org/reports/1993/6509duffus/c.htm l, (IUPAC/ Tox - Amer) {107}