Chronic Reference Dose (RfD)
Chronic Reference Dose (RfD) : An estimate (with uncertainty spanning perhaps an order of magnitude or greater) of a daily exposure level for the human population, including sensitive subpopulations, that is likely to be without an appreciable risk of harmful effects during a lifetime. Chronic RfDs are specifically developed to be protective for long-term exposure to a compound (as a Superfund program guideline, seven years to lifetime)