Acute Toxicity Test 1
Acute Toxicity Test 1 : An experimental animal study in which the adverse effects occur in a short time (from l-7 days) following the administration of a single or multiple doses of a chemical. The most frequently used acute toxicity test involves determination of the median lethal dose (LD50) of the compound. The LD50 has been defined as ''a statistically derived expression of a single administered dose of a material that can be expected to kill 50% of the animals'' (WHO, 1978a)
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