Experimental animal study to determine what adverse effects occur in a short time (usually up to 14 d) after a single dose of a substance or after multiple doses given in up to 24h. Related term: Limit Test, Median Lethal Dose (LD50)
International Union of Pure and Applied Chemistry IUPAC, Glossary for Chemists of Terms Used in Toxicology, Prepared for publication by J.H. Duffus, NC., USA 1993. http://www.inchem.org/documents/harmproj/harmproj/ harmproj1.pdf & http://old.iupac.org/reports/1993/6509duffus/c.htm l, (IUPAC/ Tox - Amer) {107}