Critical Effect 2 : The first adverse effect that appears when the critical concentration in the critical organ is reached in an individual (or the adverse effect that occurs as a result of the lowest dose in the critical organ)
International Programme on Chemical Safety IPCS (A joint venture of the United Nations Environment Programme UNEP, the International Labour Organisation, ILO and the World Health Organization WHO), Glossary of Terms on Chemical Safety for Use in IPCS Publications, World Health Organization, Division of Environmental Health, World Health Organization, Geneva, Switzerland, ILO 1996-2010. http://www.ilo.org/legacy/english/protection/safew ork/cis/products/safetytm/glossary.ht, (IPCS Chem Sfty - Brit) {103}