Medicine.  Disease. A highly infectious disease of wide distribution and great economic importance, occurring in cattle, swine, sheep, goats and all wild and domestic cloven-footed animals caused by a picornavirus (genus Rhinovirus) and characterised by vesicular eruptions in the mouth, tongue, hoofs, and udder; humans are rarely affected. Synonym: aftosa. Foot-and-mouth disease or hoof-and-mouth disease (Aphthae epizooticae) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever for two or three days, followed by blisters inside the mouth and on the feet that may rupture and cause lameness. Foot-and-mouth disease (FMD) has severe implications for animal farming, since it is highly infectious and can be spread by infected animals through aerosols, through contact with contaminated farming equipment, vehicles, clothing or feed, and by domestic and wild predators. llamas, and alpacas may develop mild symptoms, but are resistant to the disease and do not pass it on to others of the same species. which limits the effectiveness of vaccination. An OSH glossary used in safety and health at work which is, adopted by ILO  {102}. The term definition has been obtained from the secondary source