A fume or fumes refers to vapors (gases), dusts and/or smoke given off by a substance as a result of a chemical transformation such as reaction, heating, explosion or detonation. "Fumes" generally conveys the idea that the cloud is an irritating, hazardous and/or toxic substance. The term applies particularly to very fine solid particles as a suspension in air. This closely matches the definition of dust, the main difference being that fumes are airborne whereas dusts need not be suspended in the air. Additional Info: Fumes may contain both gases (vapors) and dusts. In many cases, the vapors are toxic or corrosive. For example, titanium tetrachloride (TiCl4) reacts immediately and violently with water vapor in the air to form dense white fumes. The chemical reaction that explains this behavior is: TiCl4 + 2 H2O  TiO2(s) + 4 HCl(g). The TiO2 (titania), is a solid that forms small white particles. The HCl (hydrogen chloride) is an invisible and hygroscopic gas that immediately condenses with water vapor in the air to form suspended liquid particles. The droplets in this HCl mist are acidic aqueous, solutions of hydrochloric acid. Inhalation of these fumes is dangerous because each component is hazardous. The hydrochloric acid droplets can cause chemical burns to the respiratory system, eyes and skin; the fine particles of titania further irritate the damaged tissues. MSDS Relevance: Fumes generally require more careful attention than simple dusts or vapors. For example, while a dust mask might be sufficient protection from some dusts, a dust mask will do nothing to protect you from titanium tetrachloride fumes which contain corrosive HCl. Likewise, an organic vapor respirator will not protect the user from fumes containing HCl. Therefore, always try to control or eliminate the generation of fumes in the first place. Use appropriate ventilation such as fume hoods and other engineering controls. If the fumes are not adequately controlled with these methods, always use proper personal protective equipment (PPE) such as supplied air respirators. Finally, note that many metal fumes, such as those generated in metal refining operations, soldering, and welding are significant health hazards. A general class of occupational disease is called metal fume fever. See: The links below for more info. See also: Dust, Fume Hood, Mist, Smoke