Granuloma 4


Granuloma 4 : Imprecise term applied to small nodular delimited aggregation of mononuclear inflammatory cells, or collection of modified macrophages resembling epithelial cells (epithelioid cells), usually surrounded by a rim of lymphocytes, often with multinucleated giant cells. Some granulomas contain eosinophils and plasma cells, and fibrosis is commonly seen around the lesion. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents
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