Histoplasmosis, Darling's Disease


Histoplasmosis, Darling's Disease : A fungal disease that is rarely a significant problem in those with a normal functioning immune system. This infection is more common in the southeastern, midatlantic and central states. The vast majority of infections are either asymptomatic or mild and the diagnosis can be difficult. Cough, fever, malaise and typical chest X-ray findings can occur. A serious disseminated form of the infection can occur in the immunocompromised individual (AIDS) that carries a 90% fatality rate. Histoplasmosis (also known as "Cave disease," "Spelunker’s Lung" and "Caver's disease") is a disease caused by the fungusHistoplasma capsulatum. Symptoms of this infection vary greatly, but the disease affects primarily the lungs. Occasionally, other organs are affected; this is called disseminated histoplasmosis, and it can be fatal if left untreated. Histoplasmosis is common among AIDS patients because of their suppressed immunity. In immunocompetent individuals, past infection results in partial protection against ill effects if reinfected. Histoplasmosis is found in soil, often associated with decaying bat guano or bird droppings. Disruption of soil from excavation or construction can release infectious elements that are inhaled and settle into the lung. An OSH glossary used in safety and health at work which is, adopted by ILO
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