A single dose of a material which on the basis of laboratory tests is expected to kill 50% of a group of test animals. The LD50 dose is usually expressed as milligrams or grams of material per kilogram of animal body weight (mg/kg or g/kg). References: The Center for Chemical Process Safety of th American Institute of Chemical Engineers. Safety Health, and Loss Prevention in Chemical Processes. 345 East 47th Street, New York, NY 10017, 1990