Having an affinity for fat and high lipid solubility: a physicochemical property which describes a partitioning equilibrium of solute molecules between water and an immiscible organic solvent, favouring the latter, and which correlates with bioaccumulation.Related Term: bioaccumulation, bioaccumulation factor, bioconcentration,octanol-water partition coefficient. Syn: hydrophobicity. Ant: hydrophilicity,lipophobicity