Microsome


Microsome :

Artefactual spherical particle, not present in the living cell, derived from pieces of the endoplasmic reticulum present in homogenates of tissues or cells: microsomes sediment from such homogenates when centrifuged at 100 000 g and higher: the microsomal fraction obtained in this way is often used as a source of mono-oxygenase enzymes. Related term: cytochrome P-420, cytochrome P-448, cytochrome P-450,endoplasmic reticulum, mono-xygenase, phase 1 reactions

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