Mono-oxygenase
Mono-oxygenase :
Enzyme that catalyses reactions between an organic compound and molecular oxygen in which one atom of the oxygen molecule is incorporated into the organic compound and one atom is reduced to water; involved in the metabolism of many natural and foreign compounds giving both unreactive products and products of different or increased toxicity from that of the parent compound: such enzymes are the main catalysts of phase 1 reactions in the metabolism of xenobiotics by the endoplasmic reticulum or by preparations of microsomes. Syn: mixed function oxidase. Related term: cytochrome P-420, cytochrome P-448, cytochrome P-450,endoplasmic reticulum, microsome, phase 1 reactions
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