Multistage Model
Multistage Model :
Dose-response model for cancer death estimation of the form
P(d) = 1 - exp[-(qo + q1d1+ q2d2 + ........... + q(k)dk)] where P(d) is the probability of cancer death from a continuous dose rate, d, the q's are constants, and k is the number of dose groups (or, if less than the number of dose groups, k is the number of biological stages believed to be required in the carcinogenesis process). With the multistage model, it is assumed that cancer is initiated by cell mutations in a finite series of steps. A one-stage model is equivalent to a one-hit model
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